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AttributesValues
rdf:type
rdfs:label
  • Methylmercaptopurine Riboside
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name
  • Methylmercaptopurine Riboside
NSC_Code
  • 40774
UMLS_CUI
  • C0025828
CAS_Registry
  • 342-69-8
PDQ_Open_Trial_Search_ID
  • 39497
PDQ_Closed_Trial_Search_ID
  • 39497
Legacy_Concept_Name
  • Methylmercaptopurine_Riboside
FULL_SYN
  • 6-(methylthio) inosineSNNCI
  • 9H-Purine, 6-(methylthio)-9-.beta.-D-ribofuranosyl- (8CI 9CI)SYDTPNSC0040774
  • beta-D-ribosyl-6-methylthiopurineSNNCI
  • 6-MMPRSYDTPNSC0040774
  • 6-(methylthio)purine ribonucleosideSNNCI
  • 9H-Purine, 6-(methylthio)-9-.beta.-D-ribofuranosyl-, dihydrateSYDTPNSC0040774
  • MMPRABNCI
  • 9H-purine, 6-(methylthio)-9beta-D-ribofuranosylSNNCI
  • 6-MMPRABNCI
  • methylthioinosineSYNCI
  • 9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl- (8CI 9CI)SNNCI
  • purine-6-thiol,6-methyl-9-ribofuranosylSNNCI
  • 6-(methylthio)purine ribosideSNNCI
  • 6-(methylmercapto)purine ribonucleosideSNNCI
  • Methylmercaptopurine RibosidePTNCI
  • SQ 21977CNNCI
  • 6-methylthioinosineSNNCI
  • 6-methyl MP ribosideSNNCI
  • 9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl-, dihydrateSNNCI
  • NCI-C04784CNNCI
  • 6-methylmercaptopurine ribosideSNNCI
DEFINITION
  • A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation. (NCI04)NCI
code
  • C2352
sameAs
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