About: Imipenem-Cilastatin Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Imipenem-Cilastatin Sodium
rdfs:subClassOf
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Imipenem-Cilastatin Sodium
NSC_Code
  • 717864
UMLS_CUI
  • C0733696
PDQ_Open_Trial_Search_ID
  • 40786
PDQ_Closed_Trial_Search_ID
  • 40786
Legacy_Concept_Name
  • Imipenem-Cilastatin_Sodium
FULL_SYN
  • Imipenem-Cilastatin SodiumPTNCI
  • Imipenem/Cilastatin SodiumSYNCI
  • PrimaxinSYDTPNSC0717864
  • PrimaxinBRNCI
DEFINITION
  • A parenteral antibiotic preparation containing imipenem and cilastatin sodium with bactericidal activity. Imipenem, a broad spectrum beta-lactam antibiotic, binds to penicillin-binding proteins (PBP) on the inner membrane of the bacterial cell wall, thereby interfering with the cross-linkage of peptidoglycan chains critical for bacterial cell wall strength and rigidity. Cilastatin sodium is added to reduce breakdown of imipenem by kidney dehydropeptidase. This agent is effective against both gram positive and negative bacteria and is often used in treating severe infections caused by multiresistant organisms.NCI
code
  • C2338
http://linked.open...y/mesh/hasConcept
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 18 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software