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AttributesValues
rdf:type
rdfs:label
  • Niacinamide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Vitamin
Preferred_Name
  • Niacinamide
NSC_Code
  • 13128
  • 27452
UMLS_CUI
  • C0028027
CAS_Registry
  • 98-92-0
Accepted_Therapeutic_Use_For
  • Pellegra, treatment and prophylaxis; Various dermatologic conditions
In_Clinical_Trial_For
  • Radiosensitizer, bladder cancer
FDA_UNII_Code
  • 25X51I8RD4
Contributing_Source
  • FDA
ALT_DEFINITION
  • A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Niacinamide helps some enzymes make energy in the cell. It is found in many plant and animal products. It is water-soluble (can dissolve in water) and must be taken in daily. It is being studied to increase the effect of radiation therapy on tumor cells.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42044
PDQ_Closed_Trial_Search_ID
  • 42044
Chemical_Formula
  • C6H6N2O
Legacy_Concept_Name
  • Niacinamide
CHEBI_ID
  • CHEBI:17154
FULL_SYN
  • NiacinamidePTNCI
  • NicotinamideSYNCI
  • NicotylamideSYNCI
  • Nicotinic acid amideSYDTPNSC0027452
  • niacinamidePTNCI-GLOSSCDR0000045416
  • NicotinamidumSYNCI
  • NiacinamidePTDCP02180
  • nicotinamidePTNCI-GLOSSCDR0000044441
  • Pellagra-Preventing FactorSYNCI
  • NicamidFBNCI
  • Vitamin PPSYDTPNSC0027452
  • Nicotinic Acid AmideSYNCI
  • NIACINAMIDEPTFDA25X51I8RD4
  • 3-PyridinecarboxamideSYNCI
  • Vitamin PPSYNCI
  • NicosedineFBNCI
  • NiacinamideSYDTPNSC0027452
DEFINITION
  • The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.NCI
code
  • C2327
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