About: Alfentanil Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Alfentanil Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Alfentanil Hydrochloride
UMLS_CUI
  • C0700562
CAS_Registry
  • 70879-28-6
FDA_UNII_Code
  • 11S92G0TIW
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 42783
PDQ_Closed_Trial_Search_ID
  • 42783
Chemical_Formula
  • C21H32N6O3.ClH.H2O
Legacy_Concept_Name
  • Alfentanil_Hydrochloride
FULL_SYN
  • Alfentanil HydrochloridePTNCI
  • ALFENTANIL HYDROCHLORIDEPTFDA11S92G0TIW
  • AlfentaBRNCI
  • RapifenFBNCI
DEFINITION
  • The hydrochloride salt of alfentanil, a synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking the actions of morphine, the prototypical mu receptor agonist. This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited.NCI
code
  • C220
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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