About: Adenoma of the Mouse Pulmonary System     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Adenoma of the Mouse Pulmonary System
rdfs:subClassOf
Semantic_Type
  • Neoplastic Process
Display_Name
  • Adenoma of the Pulmonary System
Preferred_Name
  • Adenoma of the Mouse Pulmonary System
UMLS_CUI
  • C1522089
ALT_DEFINITION
  • Among features indicating benign character are a small size, and absence of vascular invasion. Well delineated demarcation and absence of lepidic growth are considered by some as indicators of a benign character. Bland character of nuclei is a main feature of human adenomas. By this criterion many mouse adenomas could be assigned to adenocarcinomas. However, unlike in humans, mouse tumors are rarely metastatic during the time of their observation.MMHCC
  • Well circumscribed areas consisting of cuboidal to columnar cells lining alveoli. The size is usually less than 4 mm in diameter and retains preexisting alveolar structure. These lesions tend to be multiple in existing mouse models. Absence of pronounced fibrovascular stroma, as well as more "plump" shape of epithelial cells, may be the reason for different appearance of mouse adenomas, as compared to their human counterparts. Differentiation between a small adenoma and focal hyperplasia can be very difficult. At the same time, no absolute criteria exist for distinguishing a large adenoma from a well-differentiated adenocarcinoma.MMHCC
Legacy_Concept_Name
  • Adenoma_of_the_Mouse_Pulmonary_System
FULL_SYN
  • Adenoma of the Mouse Pulmonary SystemPTNCI
  • AdenomaSYCTRM
  • Adenoma of the Pulmonary SystemDNCTRM
Subsource
  • Nikitin et. al., Boston Recommendations for Classification of Pulmonary Proliferative Lesions of the Mouse, 2003.
code
  • C21762
is rdfs:subClassOf of
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