About: Microinvasive Carcinoma of the Mouse Prostate Gland     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Microinvasive Carcinoma of the Mouse Prostate Gland
rdfs:subClassOf
Semantic_Type
  • Neoplastic Process
Display_Name
  • Microinvasive Carcinoma of the Prostate Gland
Preferred_Name
  • Microinvasive Carcinoma of the Mouse Prostate Gland
UMLS_CUI
  • C1522414
ALT_DEFINITION
  • Conceptually the earliest forms of invasive carcinoma, with extension of malignant cells through basement membrane of HGPIN glands into surrounding thin rim of stroma. Can be difficult to distinguish from tangential sections of HGPIN glands, especially given the extensive nature of HGPIN in most models showing progression and the thin rim of stroma in mouse. Adjunctive methodologies may be warranted, especially in models not showing progression to more definitive and unequivocal invasive carcinoma.MMHCC
  • The concept of MI and being able to recognize it is important for helping define molecular alterations important for progression from HGPIN to invasive carcinoma. In human pathology, settings where this term is utilized may include prognostic implications; e.g., more favorable prognosis and minimal metastatic potential compared to greater extents of invasion. Size (in mm) or other criteria for extent of invasion are generally offered. Those in the mouse taxonomy are currently arbitrary, and the biologic significance of extent of invasion remains to be established.MMHCC
Legacy_Concept_Name
  • Microinvasive_Carcinoma_of_the_Mouse_Prostate_Gland
FULL_SYN
  • MISYCTRM
  • Microinvasive Carcinoma of the Prostate GlandDNCTRM
  • Microinvasive Carcinoma (MI)SYCTRM
  • Microinvasive Carcinoma of the Mouse Prostate GlandPTNCI
code
  • C21733
is rdfs:subClassOf of
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