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AttributesValues
rdf:type
rdfs:label
  • Monoubiquitination
rdfs:subClassOf
Semantic_Type
  • Molecular Function
Preferred_Name
  • Monoubiquitination
UMLS_CUI
  • C1513486
Legacy_Concept_Name
  • Monoubiquitination
FULL_SYN
  • MonoubiquitinationPTNCI
  • MonoubiquitinationSYNCI
DEFINITION
  • The type of ubiquitin modification determines the functional consequences for the modified protein. Monoubiquitination does not serve as a proteasome targeting signal, but plays other distinct roles. Target proteins are monoubiquitinated on one or more lysine residues, which serve as a signal for intracellular sorting as well as endocytosis of cell-surface proteins. Monoubiquitination of cell-surface receptors serves as a signal to target them to lysosome, where they are degraded by lysosomal proteases. (From PMID and NCI)NCI
code
  • C21588
is someValuesFrom of
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