About: Complement C3     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Complement C3
equivalentClass
OMIM_Number
  • 120700
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Complement C3
UMLS_CUI
  • C0009506
Legacy_Concept_Name
  • Complement_Component-3
FULL_SYN
  • C3SYNCI
  • Complement Component 3SYNCI
  • Complement C3PTNCI
  • C3 and PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 1SYNCI
Swiss_Prot
  • P01024
DEFINITION
  • Complement C3 (1663 aa, ~187 kDa) is encoded by the human C3 gene. This protein plays a role in complement-mediated immunity.NCI
DesignNote
  • Complement Component 3, encoded by the C3 gene plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacteria infection. (From LocusLink)
  • Complement C3 is cleaved into the following 10 chains: Complement C3 beta chain, Complement C3 alpha chain, C3a anaphylatoxin, Complement C3b alpha' chain, Complement C3c alpha' chain fragment 1, Complement C3dg fragment, Complement C3g fragment, Complement C3d fragment, Complement C3f fragment, and Complement C3c alpha' chain fragment 2. (UniProt)
code
  • C21527
sameAs
http://linked.open...y/mesh/hasConcept
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