About: MLN51 Protein     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • MLN51 Protein
rdfs:subClassOf
OMIM_Number
  • 606504
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Biologically Active Substance
Preferred_Name
  • MLN51 Protein
UMLS_CUI
  • C1137611
Legacy_Concept_Name
  • MLN51_Protein
FULL_SYN
  • MLN51 ProteinPTNCI
  • CASC3SYNCI
  • MLN51SYNCI
  • Metastatic Lymph Node 51 ProteinSYNCI
Swiss_Prot
  • O15234
DEFINITION
  • Encoded by human MLN51 Gene, ubiquitous cytoplasmic 76.3 kD MLN51 Protein contains 703 residues that share no significant homology with any known protein. MLN51 is well conserved between vertebrate and invertebrate species suggesting an important function. The N-terminal half contains putative nuclear localization signals and a coiled-coil domain that seems to promote MLN51 oligomerization. The C-terminal half contains a SH2 and four SH3 binding motifs and may regulate nuclear localization. The unusual combination of protein-protein interaction domains in MLN51 suggests a possible nucleo-cytoplasmic function. Malignant breast carcinoma epithelial cells exhibit over expression of MLN51. (from Oncogene 2002; 21:4422, SWISS-PROT, LocusLink, and NCI)NCI
code
  • C21525
http://linked.open...y/mesh/hasConcept
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