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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Complement Component Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • Complement Component Gene
UMLS_CUI
  • C1333135
Legacy_Concept_Name
  • Complement_Component_Gene
FULL_SYN
  • Complement Component GenePTNCI
Gene_Encodes_Product
  • Complement Component Protein
DEFINITION
  • These genes encode more than 30 proteins of the complement system engaged in host defense. This system provides both an independent immune system capable of attacking microbes as well as other foreign material and an adjunct to the antibody system. Once activated, the complement system fires in a cascade-like fashion in which one component activates the next. Both swift and powerful, millions of complement components can deposit on an invading microbe within only a few minutes. Such a potent system requires strict regulation to avoid host injury. Membrane cofactor protein (MCP) is one critical regulator aimed at controlling inadvertent complement activation on host cells and nearly every cell examined expresses MCP on its cell membrane.NCIhttp://research.medicine.wustl.edu
code
  • C21518
is rdfs:subClassOf of
is someValuesFrom of
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