About: ANP32D Protein     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • ANP32D Protein
rdfs:subClassOf
OMIM_Number
  • 606878
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Biologically Active Substance
Preferred_Name
  • ANP32D Protein
UMLS_CUI
  • C1332094
Legacy_Concept_Name
  • ANP32D_Protein
FULL_SYN
  • Acidic Nuclear Phosphoprotein 32DSYNCI
  • Acidic (Leucine-Rich) Nuclear Phosphoprotein 32 Family Member D ProteinSYNCI
  • ANP32D ProteinPTNCI
  • ANP32DSYNCI
Swiss_Prot
  • O95626
DEFINITION
  • Encoded by human ANP32D Gene, 131-amino acid 14.8 kD PP32R2 Protein (PP32 Family) shares approximately 90% amino acid sequence identity with tumor suppressor PP32 and PP32R1. PP32 can inhibit several types of cancers, including prostate and breast cancers. PP32R2 and PP32R1 are tumorigenic. Amino acids 150-174 of PP32 are responsible for its tumor suppressor function and are a region of divergence with PP32R1. Alternative use of PP32, PP32R1, and PP32R2 may modulate the oncogenic potential of human prostate cancer. PP32R2 is expressed in prostate cancer. (from SWISS-PROT, OMIM, and NCI)NCI
code
  • C21485
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