About: Beta Adrenergic Receptor Gene     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Beta Adrenergic Receptor Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • Beta Adrenergic Receptor Gene
UMLS_CUI
  • C1332546
Legacy_Concept_Name
  • Beta_Adrenergic_Receptor_Gene
FULL_SYN
  • Beta Adrenergic Receptor GenePTNCI
Gene_Encodes_Product
  • Beta Adrenergic Receptor
DEFINITION
  • Expressed in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Beta Adrenergic Receptor Genes encode Beta Adrenergic Receptors, one of two major classes of adrenergic receptors (alpha and beta) based on their reactions to norepinephrine and epinephrine, on cellular effects of receptor activation, and on relative affinities and reactions to synthetic blocking or stimulating agents. Beta-adrenergic receptors respond to blocking agents such as propranolol and to activating agents such as isoproterenol. Beta-1 type receptors mediate lipolysis and increase cardiac rate and force of contraction; beta-2 type receptor activation promotes bronchial and vascular smooth muscle relaxation. When coupled to adenylate cyclase through Gs protein, Beta Adrenergic Receptor stimulation results in increased intracellular cyclic AMP. (NCI)NCI
code
  • C21292
is rdfs:subClassOf of
is someValuesFrom of
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