About: I 131 Monoclonal Antibody Lym-1     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • I 131 Monoclonal Antibody Lym-1
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Immunologic Factor
Preferred_Name
  • I 131 Monoclonal Antibody Lym-1
UMLS_CUI
  • C1134561
In_Clinical_Trial_For
  • Aggressive B-cell Lymphoma; Previously Treated Diffuse Large Cell Lymphoma; Intermediate or High Grade Recurrent or Refractory B-cell Non-Hodgkins Lymphoma.
PDQ_Open_Trial_Search_ID
  • 38533
PDQ_Closed_Trial_Search_ID
  • 38533
Legacy_Concept_Name
  • I_131_Monoclonal_Antibody_Lym-1
FULL_SYN
  • Iodine I 131 Monoclonal Antibody Lym-1SYNCI
  • OncolymBRNCI
  • I 131 Monoclonal Antibody Lym-1PTNCI
DEFINITION
  • A radioimmunoconjugate of a murine monoclonal antibody, MoAb Lym-1, labeled with iodine 131 (I-131). MoAb Lym-1 recognizes an epitope of the histocompatibility antigen HLA-DR, which is over-expressed on most B-cell lymphomas. I-131 MoAb Lym-1 delivers beta and gamma radiation emitting I-131 nuclide directly to tumor cells that express HLA-DR, thereby allowing imaging and/or treatment of cancers.NCI
code
  • C2103
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