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AttributesValues
rdf:type
rdfs:label
  • Lopinavir
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Lopinavir
UMLS_CUI
  • C0674432
CAS_Registry
  • 192725-17-0
FDA_UNII_Code
  • 2494G1JF75
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used with another drug, called ritonavir, to treat infection with HIV (the virus that causes AIDS). It is also being studied in the treatment of some types of cancer. Lopinavir blocks the ability of HIV to make copies of itself and may help some anticancer drugs work better. It is a type of anti-HIV agent and a type of protease inhibitor.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 540623
PDQ_Closed_Trial_Search_ID
  • 540623
Chemical_Formula
  • C37H48N4O5
Legacy_Concept_Name
  • Lopinavir
FULL_SYN
  • LOPINAVIRPTFDA2494G1JF75
  • ABT-378/rCNNCI
  • LopinavirPTNCI
  • lopinavirPTNCI-GLOSSCDR0000642972
DEFINITION
  • A peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related drug ritonavir.NCI
code
  • C2095
sameAs
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