About: FABP Family Gene     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • FABP Family Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • FABP Family Gene
UMLS_CUI
  • C1333529
Legacy_Concept_Name
  • FABP_Family_Gene
FULL_SYN
  • FABP Family GenePTNCI
DEFINITION
  • These genes encode the intracellular fatty acid-binding proteins (FABPs). Fatty acid metabolism in mammalian cells depends on a flux of fatty acids, between the plasma membrane and mitochondria or peroxisomes for beta-oxidation, and between other cellular organelles for lipid synthesis. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and at least 3 different FABPs play a role as transport vehicles of these hydrophobic compounds throughout the cytoplasm. They may participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. (from LocusLink 2170)NCI
code
  • C20735
is rdfs:subClassOf of
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