About: RNA Polymerase II Subunit Gene     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • RNA Polymerase II Subunit Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • RNA Polymerase II Subunit Gene
UMLS_CUI
  • C1335628
Legacy_Concept_Name
  • RNA_Polymerase-II_Subunit_Gene
FULL_SYN
  • RNA Polymerase II Subunit GenePTNCI
DEFINITION
  • RNA polymerase II subunit genes encode DNA-dependent RNA polymerase II, a complex multisubunit enzyme that is responsible for the transcription of protein-coding genes. Ten to 14 subunits encoded by these genes range in size from 220 to 10 kD. The complex interacts with the promoter regions of genes as well as with a variety of elements and transcription factors to determine essentially all of the parameters that govern transcription, e.g., tissue and development specificity, stress response, etc. A fraction of the large subunit of Pol II (Pol II LS) is ubiquitinated after exposing cells to UV radiation or cisplatin. (NCI)NCI
code
  • C20660
is rdfs:subClassOf of
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