About: TBP-Associated Factor Gene     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • TBP-Associated Factor Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • TBP-Associated Factor Gene
UMLS_CUI
  • C1336591
Legacy_Concept_Name
  • TBP-Associated_Factor_Gene
FULL_SYN
  • TBP-Associated Factor GenePTNCI
DEFINITION
  • Control of transcription by RNA polymerase involves the basal transcription machinery, a collection of proteins which include TFIIB, TFIIE, TFIIF, TATA-box binding protein (TBP), TFIIA and TAF1. These, with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TBP-associated factors (TAFs) encoded by these TBP-Associated Factor Genes. Different TAFs may mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. (from OMIM 600772 and NCI)NCI
code
  • C20539
is rdfs:subClassOf of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 49 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software