About: Leukoregulin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Leukoregulin
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Leukoregulin
UMLS_CUI
  • C0064839
Legacy_Concept_Name
  • Leukoregulin
FULL_SYN
  • LeukoregulinPTNCI
DEFINITION
  • Secreted by activated natural killer lymphocytes as a 50-kDa glycoprotein lymphokine, Leukoregulin can up regulate the expression of hyaluronan and prostaglandin-endoperoxide H synthase 2 (PTGS2), the inflammatory cyclooxygenase. Leukoregulin shows tumor growth inhibitory activity, enhances membrane permeability, and promotes the uptake of cytotoxic drugs by tumors cells without affecting these processes in normal cells. (NCI)NCI
  • A glycoprotein of 50 kDa secreted by activated natural killer lymphocytes. Leukoregulin shows tumor growth inhibitory activity and enhances membrane permeability and the uptake of cytotoxic drugs by tumors cells without affecting these processes in normal cells. (from Cytokines Online Pathfinder Encyclopaedia)NCI
code
  • C20525
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