About: Chemokine

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Chemokine
rdfs:subClassOf	Cytokines nodeID://b658732 nodeID://b658733 nodeID://b658734 nodeID://b658735 nodeID://b658736
Semantic_Type	Amino Acid, Peptide, or Protein Immunologic Factor
Preferred_Name	Chemokine
UMLS_CUI	C0282554
ALT_DEFINITION	Class of pro-inflammatory cytokines that have the ability to attract and activate leukocytes. They can be divided into at least three structural branches: C; (CHEMOKINES, C); CC; (CHEMOKINES, CC); and CXC; (CHEMOKINES, CXC); according to variations in a shared cysteine motif.MSH2002_06_01
Legacy_Concept_Name	Chemokine
FULL_SYN	Homologous Chemotactic CytokinesSYNCI IntercrinesSYNCI SIS cytokinesSYNCI ChemokinePTNCI Chemotactic CytokinesSYNCI ChemokinesSYNCI
DEFINITION	Chemokines constitute a superfamily of small (8-10 kDa), inducible, secreted, pro-inflammatory cytokines that are involved in a variety of immune and inflammatory responses as well as in viral infection. Chemokines act primarily as chemoattractants and activators of specific types of leukocytes. Some members of this family were initially identified on the basis of their biological activities (e.g., IL-8, GRO), others were discovered using subtractive hybridization (e.g., RANTES) or signal sequence trap (e.g., PBSF/SDF-1)11 cloning strategies. They attract and activate leukocytes and regulate diverse cellular systems and organs ranging from blood vessels to the central nervous system.NCI
code	C20466
sameAs	Chemokines
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0028294
is rdfs:subClassOf of	Chemokines, CXC Chemokines, CC Chemokine, Other Chemokines, CX3C Chemokines, C
is someValuesFrom of	nodeID://b651988 nodeID://b651995 nodeID://b652244 nodeID://b656286 nodeID://b670617 nodeID://b684002 nodeID://b696687 nodeID://b703463 nodeID://b712949 nodeID://b712952
is sameAs of	Chemokines

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