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AttributesValues
rdf:type
rdfs:label
  • Acetylcysteine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Acetylcysteine
NSC_Code
  • 111180
UMLS_CUI
  • C0699252
CAS_Registry
  • 616-91-1
Accepted_Therapeutic_Use_For
  • Acetaminophen Overdose
FDA_UNII_Code
  • WYQ7N0BPYC
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug usually used to reduce the thickness of mucus and ease its removal. It is also used to reverse the toxicity of high doses of acetaminophen.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39130
PDQ_Closed_Trial_Search_ID
  • 39130
Chemical_Formula
  • C5H9NO3S
Legacy_Concept_Name
  • Acetylcysteine
CHEBI_ID
  • CHEBI:28939
FULL_SYN
  • FluimucetinSYDTPNSC0111180
  • N-Acetyl-L-cysteineSYDTPNSC0111180
  • FluimucetinFBNCI
  • MucolyticumFBNCI
  • Muco SanigenFBNCI
  • BroncholysinSYDTPNSC0111180
  • BroncholysinFBNCI
  • Neo-FluimucilFBNCI
  • ACETYLCYSTEINEPTFDAWYQ7N0BPYC
  • L-Alpha-acetamido-beta-mercaptopropionic AcidSYNCI
  • N-acetyl-L-cysteinePTNCI-GLOSSCDR0000520253
  • AcetylcysteinePTNCI
  • NACABNCI
  • N-acetyl-3-mercaptoalanineSYNCI
  • AirbronSYDTPNSC0111180
  • N-AcetylcysteineSYNCI
  • N-Acetyl CysteineSYNCI
  • RespaireSYDTPNSC0111180
  • ParvolexSYDTPNSC0111180
  • MucomystSYDTPNSC0111180
  • FabrolFBNCI
  • BrunacFBNCI
  • MucretFBNCI
  • TixairFBNCI
  • N-AcetylcysteineSYDTPNSC0111180
  • acetylcysteinePTNCI-GLOSSCDR0000045166
  • AirbronFBNCI
  • FluatoxFBNCI
  • FluimucilSYDTPNSC0111180
  • AcetylcysteinePTDCP01008
  • N-acetyl-L-cysteineSYNCI
  • RespaireFBNCI
  • ParvolexFBNCI
  • MucomystBRNCI
  • MucosolvinSYDTPNSC0111180
  • AcetadoteBRNCI
  • MucocedylFBNCI
  • FluimucilFBNCI
  • MucolatorFBNCI
  • FluprowitFBNCI
  • N-acetylcysteinePTNCI-GLOSSCDR0000045797
  • MucosolvinFBNCI
DEFINITION
  • A synthetic N-acetyl derivative of the endogenous amino acid L-cysteine, a precursor of the antioxidant enzyme glutathione. Acetylcysteine regenerates liver stores of glutathione. This agent also reduces disulfide bonds in mucoproteins, resulting in liquification of mucus. Some evidence suggests that acetylcysteine may exert an anti-apoptotic effect due to its antioxidant activity, possibly preventing cancer cell development or growth. In addition, acetylcysteine has inhibited viral stimulation by reactive oxygen intermediates, thereby producing antiviral activity in HIV patients. (NCI04)NCI
code
  • C200
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