About: Posterior Sex Combs     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Posterior Sex Combs
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Posterior Sex Combs
UMLS_CUI
  • C1256964
Legacy_Concept_Name
  • Posterior_Sex_Combs_Protein
FULL_SYN
  • Posterior Sex CombsPTNCI
DEFINITION
  • The Drosophila gene Posterior Sex Combs (Psc) encodes a ring-type zinc finger DNA binding protein (Polycomb group) involved in negative regulation of expression patterns of the antennapedia and bithorax homeotic selector gene complexes, and hence maintenance of segmental determination. Similar sequences have been identified in Homo sapiens and Mus musculus. Psc interacts genetically with z, brm, Sce, mxc, Asx, and several other genes. Mutations in Psc generate malformations of the longitudinal tracts. (from SWISS-PROT P35820, FlyBase 0005624, and NCI)NCI
code
  • C19869
http://linked.open...y/mesh/hasConcept
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