About: GVAX Lung Cancer Vaccine

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: GVAX Lung Cancer Vaccine Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	GVAX Lung Cancer Vaccine
rdfs:subClassOf	GVAX Cancer Vaccine
Semantic_Type	Pharmacologic Substance Immunologic Factor
Preferred_Name	GVAX Lung Cancer Vaccine
NSC_Code	730428
UMLS_CUI	C1328108
In_Clinical_Trial_For	Advanced non-small cell lung cancer
PDQ_Open_Trial_Search_ID	346435
PDQ_Closed_Trial_Search_ID	346435
Legacy_Concept_Name	GVAX_Lung_Cancer_Vaccine
FULL_SYN	GVAX Lung Cancer VaccinePTNCI GVAX Autologous Lung Cancer VaccineSYNCI CG8123CNNCI
DEFINITION	An autologous lung cancer vaccine consisting of patient-specific lung cancer cells genetically modified to secrete granulocyte-macrophage colony stimulating factor (GM-CSF), an immunostimulatory cytokine. GM-CSF modulates the proliferation and differentiation of a variety of hematopoietic progenitor cells with some specificity towards stimulation of leukocyte production and may reverse treatment-induced neutropenias. This agent also promotes antigen presentation, up-regulates antibody-dependent cellular cytotoxicity (ADCC), and increases interleukin-2-mediated lymphokine-activated killer cell function and may augment host antitumoral immunity. For safety, cells are irradiated prior to vaccination. (NCI04)NCI
code	C1979

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software