About: Linkage Disequilibrium Mapping     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Linkage Disequilibrium Mapping
rdfs:subClassOf
Semantic_Type
  • Molecular Biology Research Technique
Preferred_Name
  • Linkage Disequilibrium Mapping
UMLS_CUI
  • C1517888
Legacy_Concept_Name
  • Linkage_Disequilibrium_Mapping
FULL_SYN
  • Linkage Disequilibrium MappingPTNCI
DEFINITION
  • Linkage disequilibrium (LD) mapping is a procedure for determining the non-random association of alleles at two or more loci on a chromosome. It is based on the premise that regions adjacent to a gene of interest are transmitted through the generations along with that gene and can be identified by the specific pattern of markers (haplotypes) that they contain, so that detection of haplotypes that are shared more frequently among groups of individuals recruited for a disease or trait can be used to locate specific genes. Linkage-disequilibrium (LD) mapping is useful in identifying genes involved in complex diseases.NCI
code
  • C19647
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