About: 5' Nucleotidase     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • 5' Nucleotidase
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Enzyme
Preferred_Name
  • 5' Nucleotidase
UMLS_CUI
  • C0000530
Legacy_Concept_Name
  • Five_Prime_Nucleotidase
FULL_SYN
  • 5-NucleotidaseSYNCI
  • 5' NucleotidasePTNCI
  • 5'-NTSYNCI
  • 5'-N'TaseSYNCI
DEFINITION
  • A class of enzymes present in various organs and in many cells that catalyze the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. Serum 5'-N'Tase is measured as an indicator of liver damage resulting primarily from interference with the secretion of bile. Serum 5'-N'Tase is not as sensitive as some other enzymes (for example, ALP, AST, and ALT) to liver damage, but it is a more liver-specific enzyme. The level of this enzyme parallels alkaline phosphatase (ALP). It is used mostly to differentiate elevations in the above enzymes due to liver damage from damage to skeletal muscle.NCI
code
  • C19637
sameAs
http://linked.open...y/mesh/hasConcept
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