About: Drosophila Patched Gene     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Drosophila Patched Gene
rdfs:subClassOf
GenBank_Accession_Number
  • NM_078937
Semantic_Type
  • Gene or Genome
Preferred_Name
  • Drosophila Patched Gene
UMLS_CUI
  • C1333314
Legacy_Concept_Name
  • Drosophila_Patched_Gene
FULL_SYN
  • Drosophila Patched GenePTNCI
DEFINITION
  • Drosophila Patched Gene (Patched Family) encodes Patched protein, an integral membrane protein containing an SSD domain that acts as a segmentation polarity pattern receptor for hedgehog during embryonic segmentation and during imaginal disk development. Patched associates with smoothened protein to transduce hedgehog signal, leading to activation of wingless, decapentaplegic, and patched. In the absence of hedgehog, patched represses constitutive smoothened signaling through fused. (NCI)NCI
code
  • C18757
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