About: BCL1 Oncogene     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:DeprecatedClass, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • BCL1 Oncogene
rdfs:subClassOf
OMIM_Number
  • 168461
Semantic_Type
  • Gene or Genome
Preferred_Name
  • BCL1 Oncogene
OLD_PARENT
  • CCND1_Gene
OLD_KIND
  • Gene_Kind
OLD_ROLE
  • Gene_Associated_With_Disease|B-Cell_Leukemia
  • Gene_In_Chromosomal_Location|_11q13
Concept_Status
  • Retired_Concept
FULL_SYN
  • BCL1 OncogenePTNCI
  • B-Cell Chronic Lymphocytic Leukemia Associated OncogeneSYNCI
  • BCLSYNCI
  • B-cell Leukemia 1SYNCI
DEFINITION
  • Human cyclin D1 (BCL1) proto-oncogene, located at 11q13, encodes G1/S-specific cyclin D1 (CCND1) protein. BCL1 gene expression is activated in human B-cell lymphomas by translocation, t(11;14)(q13;q32), with immunoglobulin gene regions. Enhanced expression of cyclin D1 protein has also been detected in parathyroid adenomas due to a translocation, t(11;11)(q13;p15), resulting in fusion of BCL1 with the parathyroid hormone enhancer.NCI
code
  • C18512
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