About: Oncogenes, Tyrosine-Kinase

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About: Oncogenes, Tyrosine-Kinase Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Oncogenes, Tyrosine-Kinase
rdfs:subClassOf	Oncogenes, Protein-Kinase nodeID://b721667 nodeID://b721668
Semantic_Type	Classification Gene or Genome
Preferred_Name	Oncogenes, Tyrosine-Kinase
UMLS_CUI	C0812221
Legacy_Concept_Name	Tyrosine-Kinase_Oncogene
FULL_SYN	Oncogenes, Tyrosine-KinasePTNCI
DEFINITION	Activated forms of tyrosine kinase family proto-oncogenes that contribute to the development of cancer. These proto-oncogenes encode tyrosine kinase proteins, which are enzymes that play a major role in mitogenic signaling by catalyzing the phosphorylation of tyrosine residues in proteins. Tyrosine kinase oncogenes exhibit aberrant gene expression, resulting in elevated levels of their protein products which disrupts mitotic checkpoints.NCI
code	C18344
is rdf:first of	nodeID://b736359 nodeID://b736360 nodeID://b736361 nodeID://b736362 nodeID://b736363 nodeID://b736364 nodeID://b736365 nodeID://b736366
is rdfs:subClassOf of	ERB Oncogene Family SRC Family Oncogene

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