About: Thymosin Beta-15     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Thymosin Beta-15
rdfs:subClassOf
OMIM_Number
  • 601587
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Thymosin Beta-15
UMLS_CUI
  • C0532005
Legacy_Concept_Name
  • Thymosin_Beta-15
FULL_SYN
  • Thymosin Beta-15PTNCI
  • TMSB15SYNCI
DEFINITION
  • Thymosin beta-15, a member of the thymosin-beta family, is an actin-binding protein that enhances cell motility. It is expressed in advanced prostate cancer, but not in the normal prostate or in benign prostatic hyperplasia, suggesting its potential as a marker for prostate carcinoma progression. Thymosin-beta-15 levels correlate with the Gleason tumor grade. Thymosin-beta-15 and the motility suppressor KAI1 may provide alternate pathway targets for cancer therapy. (from OMIM 601587 and NCI)NCI
DesignNote
  • Protein_Family: Thymosin-Beta Family
  • Protein_Interacts_With: Actin, Putative
  • Protein_Malfunction_Associated_With_Disease: Metastasis
  • Protein_Has_Biochemical_Function: Actin-Binding Protein, Putative
code
  • C18041
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