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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Etaracizumab
equivalentClass
Has_Target
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Immunologic Factor
Preferred_Name
  • Etaracizumab
NSC_Code
  • 719850
UMLS_CUI
  • C2350723
CAS_Registry
  • 892553-42-3
In_Clinical_Trial_For
  • Androgen-independent prostate cancer
FDA_UNII_Code
  • 41W9MFI160
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance being studied in the treatment of some types of cancer and other conditions. Abegrin binds to a protein on the surface of blood vessels and may prevent the growth of new blood vessels that tumors need to grow. It may also prevent the spread of cancer. It is a type of antiangiogenesis agent, a type of metastasis inhibitor, and a type of monoclonal antibody.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 38491
PDQ_Closed_Trial_Search_ID
  • 38491
Legacy_Concept_Name
  • Vitaxin
FULL_SYN
  • ETARACIZUMABPTFDA41W9MFI160
  • humanized monoclonal antibody MEDI-522PTNCI-GLOSSCDR0000633069
  • EtaracizumabPTNCI
  • Humanized Monoclonal Antibody LM609SYNCI
  • etaracizumabPTNCI-GLOSSCDR0000633070
  • Monoclonal Antibody Anti-Avb3 Integrin Medi-522SYNCI
  • Monoclonal Antibody Anti-alpha V Beta 3 Integrin MEDI-522SYNCI
  • AbegrinPTNCI-GLOSSCDR0000641719
  • MEDI-522PTNCI-GLOSSCDR0000633068
  • AbegrinBRNCI
  • MEDI-522CNNCI
  • VitaxinAQSNCI
DEFINITION
  • A humanized monoclonal IgG1 antibody directed against the vitronectin receptor alpha v beta 3 integrin. Etaracizumab blocks the binding of ligands, such as vitronectin, to alpha v beta 3 integrin, resulting in inhibition of angiogenesis and metastasis. Alpha v beta 3 integrin is a cell adhesion and signaling receptor that is expressed on the surface of tumor vessel endothelial cells, some tumor cells, and a number of other cell types.NCI
code
  • C1800
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