About: Netrin Receptor DCC     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Netrin Receptor DCC
rdfs:subClassOf
OMIM_Number
  • 120470
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Netrin Receptor DCC
UMLS_CUI
  • C0289848
Legacy_Concept_Name
  • DCC_Protein
FULL_SYN
  • DCCSYNCI
  • CRC18SYNCI
  • Tumor Suppressor Protein DCCSYNCI
  • Immunoglobulin Superfamily DCC Subclass Member 1SYNCI
  • Colorectal Cancer SuppressorSYNCI
  • Deleted in Colorectal Carcinoma ProteinSYNCI
  • Netrin Receptor DCCPTNCI
Swiss_Prot
  • P43146
DEFINITION
  • Netrin receptor DCC (1447 aa, ~158 kDa) is encoded by the human DCC gene. This protein is involved in both axonal guidance and the regulation of apoptosis.NCI
DesignNote
  • Netrin receptor DCC is a transmembrane protein of the immunoglobulin superfamily, is expressed on spinal commissural axons and possesses netrin-1-binding activity. Knockout studies in mice failed to support a tumor-suppressor function for DCC in the mouse, but were consistent with the hypothesis that DCC is a component of the receptor for netrin-1, a neuronal chemoattractant. (from OMIM)
code
  • C17908
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