About: BHLH Protein

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	BHLH Protein
rdfs:subClassOf	DNA-Binding Proteins nodeID://b648712 nodeID://b648713 nodeID://b648714
Semantic_Type	Amino Acid, Peptide, or Protein
Preferred_Name	BHLH Protein
UMLS_CUI	C0288972
Legacy_Concept_Name	BHLH_Protein
FULL_SYN	BHLH ProteinPTNCI bHLH ProteinSYNCI Basic HLH ProteinSYNCI Basic Helix-Loop-Helix ProteinSYNCI
DEFINITION	bHLH class proteins are sequence-specific DNA-binding proteins that contain a conserved 50-amino acid HLH domain consisting of two alpha-helices separated by a variable loop sequence, adjacent to a sequence that is highly enriched in basic amino acids. The HLH region mediates protein dimerization, while the basic region mediates sequence-specific DNA binding. Many bHLH proteins recognize a DNA sequence known as the E box. Class A bHLH proteins are ubiquitously expressed, while class B bHLH proteins are expressed in specific cell types. In general, class B proteins preferentially bind to DNA as heterodimers with class A proteins and function as transcriptional activators.NCI
code	C17906
sameAs	Basic Helix-Loop-Helix Transcription Factors
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0481850
is someValuesFrom of	nodeID://b656680 nodeID://b665350 nodeID://b665359 nodeID://b670223 nodeID://b679237 nodeID://b680996 nodeID://b696523 nodeID://b716007 nodeID://b716621 nodeID://b720177 nodeID://b720198 nodeID://b720237 nodeID://b720384 nodeID://b720393
is sameAs of	Basic Helix-Loop-Helix Transcription Factors

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