About: p59-HCK     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:DeprecatedClass, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • p59-HCK
rdfs:subClassOf
OMIM_Number
  • 142370
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Enzyme
Preferred_Name
  • p59-HCK
OLD_PARENT
  • SRC_Family_Tyrosine_Kinase
OLD_ROLE
  • Gene_Product_Is_Element_In_Pathway some 'GPCR Signaling Pathway'
  • Gene_Product_Plays_Role_In_Biological_Process some 'Signal Transduction'
  • Gene_Product_Encoded_By_Gene some 'HCK Gene'
  • Gene_Product_Expressed_In_Tissue some B-Lymphocyte
  • Gene_Product_Expressed_In_Tissue some Granulocyte
  • Gene_Product_Has_Structural_Domain_Or_Motif some 'SH2 Domain'
  • Gene_Product_Plays_Role_In_Biological_Process some 'Tyrosine Phosphorylation'
  • Gene_Product_Plays_Role_In_Biological_Process some 'Cellular Migration Process'
  • Gene_Product_Has_Biochemical_Function some 'Protein Tyrosine Kinase'
  • Gene_Product_Is_Element_In_Pathway some 'HIV-1 Infection Pathway'
UMLS_CUI
  • C0084219
Concept_Status
  • Retired_Concept
Legacy_Concept_Name
  • p59-HCK
FULL_SYN
  • HCKSYNCI
  • Hemopoietic Cell Kinase p59SYNCI
  • p59-HCKPTNCI
Swiss_Prot
  • P08631
DEFINITION
  • Encoded by the HCK proto-oncogene, HCK appears to be a SRC-family tyrosine kinase, expressed primarily in hematopoietic cells, especially of myeloid lineage and particularly in mature granulocytes and monocytes. HCK deletions may contribute to some acute myeloid leukemias and myeloproliferative disorders. (from OMIM 142370 and NCI)NCI
DesignNote
  • Thu Sep 27 16:36:08 EDT 2012 - See 'p60-HCK'
code
  • C17899
http://linked.open...y/mesh/hasConcept
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