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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Nuclear Receptor
equivalentClass
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Receptor
Preferred_Name
  • Nuclear Receptor
UMLS_CUI
  • C0206588
Legacy_Concept_Name
  • Nuclear_Receptor
FULL_SYN
  • Nuclear ReceptorPTNCI
  • Receptor, NuclearSYNCI
DEFINITION
  • Proteins that regulate transcription via interaction with chromatin and basal transcription machinery at the promoter regions of genes. Nuclear receptors are ligand-dependent transcription factors including steroids, retinoids, vitamin D, unliganded thyroid hormone, and orphan receptors (unknown ligands). Coregulators (coactivators or corepressors) are important in mediating these interactions and thereby modulate positive or negative receptor activity.NCI
code
  • C17671
http://linked.open...y/mesh/hasConcept
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