About: Nuclear Receptor

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Nuclear Receptor
equivalentClass	nodeID://b636249
Semantic_Type	Amino Acid, Peptide, or Protein Receptor
Preferred_Name	Nuclear Receptor
UMLS_CUI	C0206588
Legacy_Concept_Name	Nuclear_Receptor
FULL_SYN	Nuclear ReceptorPTNCI Receptor, NuclearSYNCI
DEFINITION	Proteins that regulate transcription via interaction with chromatin and basal transcription machinery at the promoter regions of genes. Nuclear receptors are ligand-dependent transcription factors including steroids, retinoids, vitamin D, unliganded thyroid hormone, and orphan receptors (unknown ligands). Coregulators (coactivators or corepressors) are important in mediating these interactions and thereby modulate positive or negative receptor activity.NCI
code	C17671
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0027372
is rdf:first of	nodeID://b731557 nodeID://b731558 nodeID://b731559 nodeID://b731560 nodeID://b731561 nodeID://b731562 nodeID://b731563 nodeID://b731564 nodeID://b731565 nodeID://b731566 nodeID://b731567 nodeID://b731568 nodeID://b731569
is rdfs:subClassOf of	Receptors, Thyroid Hormone Receptors, Retinoic Acid Retinoid X Receptors Steroid Hormone Receptor Orphan Nuclear Receptors
is someValuesFrom of	nodeID://b677042 nodeID://b698290 nodeID://b704347 nodeID://b715982 nodeID://b723046

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