About: Pentosan Polysulfate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Pentosan Polysulfate
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Carbohydrate
  • Pharmacologic Substance
Preferred_Name
  • Pentosan Polysulfate
UMLS_CUI
  • C0030888
CAS_Registry
  • 37300-21-3
  • 39432-58-1
FDA_UNII_Code
  • F59P8B75R4
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to relieve pain or discomfort associated with chronic inflammation of the bladder. It is also being evaluated for its protective effects on the gastrointestinal tract in people undergoing radiation therapy.NCI-GLOSS
Chemical_Formula
  • (C5H8O10S2)n
Legacy_Concept_Name
  • Pentosan_Polysulfate
FULL_SYN
  • PENTOSAN POLYSULFATEPTFDAF59P8B75R4
  • Xylan Hydrogen SulfateSYNCI
  • pentosan polysulfatePTNCI-GLOSSCDR0000045294
  • Xylan PolysulfateSYNCI
  • CB-8061CNNCI
  • Pentosan PolysulfatePTNCI
DEFINITION
  • A semisynthetic heparin-like glucosaminoglycan. Although its mechanism of action is unknown, pentosan polysulfate may act as a buffer to control cell permeability by preventing irritating solutes from reaching cells coated with it. Administered orally, excreted pentosan polysulfate adheres to the urinary bladder wall, preventing irritants from entering bladder cells and the development or progression of interstitial cystitis (IC), a complication of some chemotherapies. This agent also exhibits anticoagulant and fibrinolytic properties. (NCI04)NCI
code
  • C1755
sameAs
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