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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Aptamer
rdfs:subClassOf
Semantic_Type
  • Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name
  • Aptamer
UMLS_CUI
  • C0599013
Legacy_Concept_Name
  • Aptamer
FULL_SYN
  • AptamerPTNCI
DEFINITION
  • Double-stranded DNA or single-stranded RNA oligonucleotide sequences with the capacity to recognize target molecules with high affinity and specificity. Fundamentally distinct from antibodies, aptamers mimic their properties and have emerged as a promising class of molecules in both therapeutic and diagnostic formats. In having small size (8-15 kDa) relative to antibodies (150 kDa), aptamers are candidates for rapid tumor penetration and blood clearance.NCI
code
  • C1749
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