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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Vitamin D3 Receptor
equivalentClass
OMIM_Number
  • 601769
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Receptor
Preferred_Name
  • Vitamin D3 Receptor
UMLS_CUI
  • C0108082
ALT_DEFINITION
  • use for receptors of any of the D vitamins.CSP2000
Legacy_Concept_Name
  • Vitamin-D3_Receptor
FULL_SYN
  • VDRSYNCI
  • 1,25-Dihydroxyvitamin D3 ReceptorSYNCI
  • Cholecalciferol ReceptorSYNCI
  • Nuclear Receptor Subfamily 1 Group I Member 1SYNCI
  • Vitamin D3 ReceptorPTNCI
  • Calcitriol ReceptorSYNCI
  • Receptors, CalcitriolSYNCI
Swiss_Prot
  • P11473
DEFINITION
  • Vitamin D3 receptor (427 aa, ~48 kDa) is encoded by the human VDR gene. This protein is involved in vitamin D-mediated transcriptional regulation.NCI
DesignNote
  • Vitamin D3 Receptors are cytoplasmic polypeptides that specifically bind 1,25(OH)2D3, migrate to the nucleus, and regulate transcription of specific target genes to produce a variety of biologic effects. The VDR protein belongs to the steroid superfamily of trans-acting transcriptional regulatory factors and is most closely related to the thyroid hormone receptors. VDR residues immediately N-terminal of the first DNA-binding zinc finger are vital for contact with TFIIB. (from OMIM 601769)
  • Vitamin D3 receptor dimerizes with retinoic acid receptor RXR-alpha after vitamin D binds. (UniProt)
code
  • C17485
sameAs
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