About: Integrin Alpha-L     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Integrin Alpha-L
equivalentClass
OMIM_Number
  • 153370
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Receptor
  • Immunologic Factor
Preferred_Name
  • Integrin Alpha-L
UMLS_CUI
  • C0079091
Legacy_Concept_Name
  • Integrin_Alpha-L
FULL_SYN
  • Alpha L Integrin ChainSYNCI
  • Lymphocyte Function-Associated Antigen-1 Alpha ChainSYNCI
  • Lymphocyte Function-Associated Antigen-1, Alpha SubunitSYNCI
  • Integrin Alpha-LPTNCI
  • CD11ASYNCI
  • ITGALSYNCI
Swiss_Prot
  • P20701
DEFINITION
  • Integrin alpha-L (1170 aa, 129 kD) is a cell motility process protein that is encoded by the human ITGAL gene and has a role in cell motility.NCI
DesignNote
  • Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGAL encodes the integrin alpha L chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. (from LocusLink)
code
  • C17372
sameAs
http://linked.open...y/mesh/hasConcept
is sameAs of
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