About: Tenascin C     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tenascin C
rdfs:subClassOf
equivalentClass
OMIM_Number
  • 187380
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Biologically Active Substance
Preferred_Name
  • Tenascin C
UMLS_CUI
  • C0076088
Legacy_Concept_Name
  • Tenascin-C
FULL_SYN
  • HexabrachionSYNCI
  • TNCSYNCI
  • TenacinSYNCI
  • CytotacinSYNCI
  • Tenascin CPTNCI
Swiss_Prot
  • P24821
DEFINITION
  • Tenascin C (2,201 aa, 241 kD) is a cell adhesion process protein that is encoded by the human TNC gene and has a role in cell adhesion.NCI
DesignNote
  • Hexameric extracellular matrix glycoprotein transiently expressed in many developing organs and often re-expressed in tumors. It is present in the central and peripheral nervous systems as well as in smooth muscle and tendons.
  • Tenascin (hexabrachion, cytotactin) is an extracellular matrix protein that promotes cell attachment with spatially and temporally restricted tissue distribution in many developing organs. It is a hexameric, multidomain protein with disulfide-linked subunits. A C-terminal domain is similar to fibrinogen. Tenascin also contains type III units, similar to those in fibronectin, and EGF-like repeats. In the CNS, tenascin C is expressed primarily by astrocytes. Tenascin expression is induced by serum as well as TGF-beta.
code
  • C17338
sameAs
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