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AttributesValues
rdf:type
rdfs:label
  • Voriconazole
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Voriconazole
UMLS_CUI
  • C0393080
CAS_Registry
  • 137234-62-9
Accepted_Therapeutic_Use_For
  • Aspergillosis, invasive; Esophageal candidiasis; Fungal infections, non-aspergillosis
In_Clinical_Trial_For
  • Fungal infections
FDA_UNII_Code
  • JFU09I87TR
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that treats infections caused by fungi.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42690
PDQ_Closed_Trial_Search_ID
  • 42690
Chemical_Formula
  • C16H14F3N5O
Legacy_Concept_Name
  • Voriconazole
CHEBI_ID
  • CHEBI:10023
FULL_SYN
  • VORICONAZOLEPTFDAJFU09I87TR
  • VoriconazolePTNCI
  • (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-olSNNCI
  • voriconazolePTNCI-GLOSSCDR0000045544
  • VfendBRNCI
DEFINITION
  • A synthetic triazole with antifungal activity. Voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. (NCI04)NCI
code
  • C1707
sameAs
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