About: Integrin

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Integrin
rdfs:subClassOf	Protein or Riboprotein Complex nodeID://b682879 nodeID://b682880 nodeID://b682881 nodeID://b682882 nodeID://b682883 nodeID://b682884
Semantic_Type	Amino Acid, Peptide, or Protein Receptor
Preferred_Name	Integrin
UMLS_CUI	C0021701
ALT_DEFINITION	family of integral membrane proteins which serve as receptors for fibronectin, laminin, and other adhesive extracellular glycoproteins.CSP2000
Legacy_Concept_Name	Integrin RGD_Receptor
FULL_SYN	RGD ReceptorSYNCI IntegrinPTNCI Extracellular Matrix, IntegrinsSYNCI
DEFINITION	Integrins are transmembrane glycoprotein receptors that mediate cell-matrix or cell-cell adhesion, and transduce signals that regulate gene expression and cell growth. They are heterodimeric molecules consisting of noncovalently linked alpha and beta subunits. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Both alpha and beta subunits display a cytoplasmic domain that interacts with the cytoskeleton (and possibly signaling molecules), a transmembrane region, and a large extracellular domain that interacts with the extracellular matrix. (from OMIM 147557)NCI
code	C16748
sameAs	Integrins
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0024497
is rdfs:subClassOf of	Integrin AlphaM/Beta2 Platelet Glycoprotein GPIIb-IIIa Complex Integrin alpha4beta1 Lymphocyte Function-Associated Antigen-1 Integrin alphaVbeta3 Integrin Alpha-V Beta-5 Protein
is someValuesFrom of	nodeID://b682082 nodeID://b682893 nodeID://b682927 nodeID://b682930 nodeID://b682941 nodeID://b682950 nodeID://b682958 nodeID://b682966 nodeID://b683010 nodeID://b683016 nodeID://b683021 nodeID://b683028 nodeID://b683031
is sameAs of	Integrins

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