About: Canonical HMG Protein

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Canonical HMG Protein
rdfs:subClassOf	Protein Family nodeID://b656600 nodeID://b656601 nodeID://b656602 nodeID://b656603 nodeID://b656604 nodeID://b656605
Semantic_Type	Amino Acid, Peptide, or Protein Biologically Active Substance
Preferred_Name	Canonical HMG Protein
UMLS_CUI	C0019534
Legacy_Concept_Name	Canonical_HMG_Protein
FULL_SYN	Archetypal HMG ProteinSYNCI HMG ProteinSYNCI High Mobility Group ProteinSYNCI HMG Motif ProteinSYNCI HMG Nuclear ProteinSYNCI Canonical HMG ProteinPTNCI
DEFINITION	The High Mobility Group (HMG) proteins were originally isolated from mammalian cells, named according to their electrophoretic mobility in polyacrylamide gels, and were arbitrarily classed as a specific type of non-histone proteins based on the observation that they are ubiquitous to mammalian cells, that they share certain physical properties, and that they are associated with isolated chromatin. Those mammalian proteins considered to be Canonical HMG proteins are now subdivided into 3 superfamilies: the HMGB (formerly HMG-1/-2) family, the HMGN (formerly HMG-14/-17) family, and the HMGA (formerly HMG-I/Y/C) family. Each HMG family has a characteristic functional sequence motif. (www.informatics.jax.org/mgihome/nomen/genefamilies/hmgfamily.shtml)NCI
DesignNote	HMG proteins regulate transcription by influencing chromatin remodeling and DNA topology.
code	C16677
sameAs	High Mobility Group Proteins
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0010347
is rdf:first of	nodeID://b741750 nodeID://b741751 nodeID://b741752
is sameAs of	High Mobility Group Proteins

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