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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Heat Shock Protein
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Heat Shock Protein
UMLS_CUI
  • C0018850
ALT_DEFINITION
  • family of highly conserved, specific proteins produced by prokaryotic and eukaryotic cells in response to heat shock or other stressor; some may protect other proteins from denaturation or degradation.CSP2000
  • One of a group of proteins that help protect cells from stresses such as heat, cold, and low amounts of oxygen or glucose (sugar). Heat-shock proteins help other proteins function in normal cells and may be present at high levels in cancer cells. Blocking the activity of a heat-shock protein called HSP90 is being studied in the treatment of cancer. Other heat-shock proteins including HSP70 and gp96 are being studied in vaccines to treat cancer.NCI-GLOSS
Legacy_Concept_Name
  • Heat_Shock_Protein
FULL_SYN
  • HSPPTNCI-GLOSSCDR0000617665
  • heat-shock proteinPTNCI-GLOSSCDR0000617664
  • HSPSYNCI
  • stress proteinPTNCI-GLOSSCDR0000617666
  • Heat Shock ProteinPTNCI
  • Heat Shock ProteinsSYNCI
DEFINITION
  • A family of highly-conserved proteins that are synthesized in response to hyperthermia (heat shock), hypoxia, or other stresses that appear to increase cellular thermal tolerance and enable cells to recover from stress. Some heat shock proteins may protect other proteins from denaturation, degradation or perform functions essential to cell survival under these conditions.NCI
code
  • C16672
sameAs
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