About: Tecogalan Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tecogalan Sodium
rdfs:subClassOf
Semantic_Type
  • Carbohydrate
  • Pharmacologic Substance
Preferred_Name
  • Tecogalan Sodium
UMLS_CUI
  • C0212199
PDQ_Open_Trial_Search_ID
  • 42149
PDQ_Closed_Trial_Search_ID
  • 42149
Legacy_Concept_Name
  • Tecogalan_Sodium
FULL_SYN
  • Tecogalan SodiumPTNCI
  • SP-PGABNCI
  • DS-4152CNNCI
  • Sulfated Polysaccharide Tecogalan DS-4152SYNCI
DEFINITION
  • A sulfated polysaccharide isolated from various Arthrobacter bacterial species. Possessing potential antiangiogenic and antineoplastic properties, tecogalan binds to basic fibroblast growth factor (bFGF), thereby preventing bFGF from binding to its receptors. Disruption of this receptor binding results in the inhibition of bFGF-stimulated endothelial cell growth, proliferation, and migration. (NCI04)NCI
code
  • C1605
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