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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Satraplatin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Inorganic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Satraplatin
UMLS_CUI
  • C1142934
CAS_Registry
  • 129580-63-8
In_Clinical_Trial_For
  • Metastatic Breast Cancer, Non-Small Cell Lung; Lung Cancer, Prostate Cancer, Hormone Refractory Prostate Cancer, One Prior Cytotoxic Chemotherapy Regimen
FDA_UNII_Code
  • 8D7B37T28G
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance being studied in the treatment of prostate and other types of cancer. It contains the metal platinum and may kill cancer cells by damaging their DNA and stopping them from dividing. It is a type of alkylating agent.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42141
PDQ_Closed_Trial_Search_ID
  • 42141
Chemical_Formula
  • C6H13N.2C2H3O2.2Cl.Pt.H3N
Legacy_Concept_Name
  • Satraplatin
FULL_SYN
  • SatraplatinPTNCI
  • (OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)platinumSNNCI
  • satraplatinPTNCI-GLOSSCDR0000367462
  • JM 216PTNCI-GLOSSCDR0000367461
  • platinum,bis(acetato-O)amminedichloro(cyclohexanamine)-,(OC-6-43)SNNCI
  • JM-216CNNCI
  • OrplatnaBRNCI
  • BMY-45594CNNCI
  • BMS-182751PTNCI-GLOSSCDR0000045425
  • SATRAPLATINPTFDA8D7B37T28G
  • (OC-6-43)-bis(acetato)amminedichloro(cyclohexylamine)platinumSNNCI
DEFINITION
  • An orally administered third generation platinum compound with potential antineoplastic activity. Satraplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in cell growth inhibition and apoptosis.NCI
code
  • C1493
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