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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Dexniguldipine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Dexniguldipine
UMLS_CUI
  • C0208704
CAS_Registry
  • 120054-86-6
FDA_UNII_Code
  • N9DG6ZTC43
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 41341
PDQ_Closed_Trial_Search_ID
  • 41341
Chemical_Formula
  • C36H39N3O6
Legacy_Concept_Name
  • Dexniguldipine
FULL_SYN
  • (S)-(+)-Watanidipine HydrochlorideSYNCI
  • DEXNIGULDIPINEPTFDAN9DG6ZTC43
  • Dexniguldipine.HClPTDCP20026
  • ((-)-3-Methyl-5- 3-(4,4-diphenyl-l-piperidinyl)-propyl-l,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylate-hydrochloride)SNNCI
  • DexniguldipinePTNCI
  • DNIGABNCI
  • Dexniguldipine HydrochlorideSYNCI
  • B859 35CNNCI
  • (R)-Nigaldipine HydrochlorideSYNCI
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid, 3-(4,4-Diphenyl-1-piperidinyl)propyl Methyl Ester, Monohydrochloride (R)-SNNCI
  • B 859-35CNNCI
  • B8509-035CNNCI
DEFINITION
  • Dexniguldipine is the (+)-enantiomer of the dihydropyridine derivate niguldipine. Dexniguldipine showed a binding affinity to the P-glycoprotein and therefore it is to be assumed to block the P-glycoprotein pumping mechanism and to modulate multidrug resistance. (NCI)NCI
code
  • C1465
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