About: FVB/N Mouse     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • FVB/N Mouse
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Mammal
Preferred_Name
  • FVB/N Mouse
UMLS_CUI
  • C1517102
Contributing_Source
  • CDISC
ALT_DEFINITION
  • NIH general purpose Swiss mice were selected for resistance or sensitivity to histamine challenge following pertussis vaccination. The sensitive strain, HFSF/N, was subsequently found to have the Fv1b allele, which sensitizes the mice to B strain Friend Leukemia virus. The FVB/N strain has an albino coat with genotype A,B,c,D,P, and has a vigorous reproductive performance.CDISC
MGI_Accession_ID
  • MGI:2160001
Legacy_Concept_Name
  • FVB_N
FULL_SYN
  • FVB/N MousePTNCI
  • FVB/NPTJAX
  • FVB/NPTCDISC
DEFINITION
  • NIH general purpose Swiss mice were selected for resistance or sensitivity to histamine challenge following pertussis vaccination. The sensitive strain, HFSF/N, was subsequently found to have the Fv1b allele, which sensitizes the mice to B strain Friend Leukemia virus. The FVB/N strain has an albino coat with genotype A,B,c,D,P, and has a vigorous reproductive performance. This strain is commonly used in the generation of transgenic mice due to the fact that the pronuclei of FVB/N fertilized oocytes are prominent, which allows for ease of microinjection.NCI
code
  • C14474
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