About: F344, Rat Strain

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About: F344, Rat Strain Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	F344, Rat Strain
rdfs:subClassOf	Common Rattus Norvegicus Strains
Concept_In_Subset	Clinical Data Interchange Standards Consortium Terminology CDISC SEND Terminology CDISC SEND Laboratory Animal Strain Terminology
Semantic_Type	Mammal
Preferred_Name	F344, Rat Strain
UMLS_CUI	C0034703
Contributing_Source	CDISC
ALT_DEFINITION	Derived by Curtiss and Dunning (1920) at Columbia University and disseminated to Heston (1949) and then to the NIH (1951). The Fischer 344 rat has an albino coat and genotype c.CDISC
Legacy_Concept_Name	F344_Rat_Strain
FULL_SYN	Fischer 344SYNCI FISCHER 344PTCDISC F344SYNCI F344, Rat StrainPTNCI
DEFINITION	Most animals older than 2 years exhibit small local areas of nephritis; less than 25% show severe nephritis (Snell 1967). Tumors: Mammary tumors 41% in females and 23% in males, pituitary adenomas 36% in females and 24% in males, testicular interstitial cell tumors 85% in males. Other tumor types less common (Sass et al 1975). Thyroid carcinoma 22% (Lindsey et al 1968). Interstitial cell testicular tumors 65%, mononuclear cell leukemia 24%, subcutaneous fibroadenoma 9% in females. Both sexes have a 5% incidence of nodular hyperplasia of the liver.NCI
code	C14401
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0018519

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