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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Vapreotide
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Vapreotide
PubMedID_Primary_Reference
  • 16917205
UMLS_CUI
  • C0164678
CAS_Registry
  • 103222-11-3
In_Clinical_Trial_For
  • Pancreatic Resection; Esophageal Varices
FDA_UNII_Code
  • 2PK59M9GFF
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called somatostatin analogs.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 38258
PDQ_Closed_Trial_Search_ID
  • 38258
Chemical_Formula
  • C57H70N12O9S2
Legacy_Concept_Name
  • Vapreotide
FULL_SYN
  • vapreotidePTNCI-GLOSSCDR0000045008
  • RC-160CNNCI
  • VAPREOTIDEPTFDA2PK59M9GFF
  • DocrisedFBNCI
  • BMY-41606CNNCI
  • VapreotidePTNCI
DEFINITION
  • A synthetic cyclic octapeptide analogue of somatostatin with direct and indirect antitumor effects. Vapreotide binds to somatostatin receptors (SSTR), specifically SSTR-2 and to SSTR-5 with a lesser affinity, in the similar behaviors as other octapeptide somatostatin analogues. Like octreotide, this agent has direct and indirect antitumor effects via inhibiting the release of growth hormone and other peptides that regulate release of insulin, gastrointestinal hormones. Furthermore, vapreotide may also be useful for inducing hemostasis in cases of acute hemorrhage of the upper gastrointestinal tract.NCI
code
  • C1429
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