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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Rifabutin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Rifabutin
UMLS_CUI
  • C0140575
CAS_Registry
  • 72559-06-9
Accepted_Therapeutic_Use_For
  • Prevention and treatment of Mycobacterium avium complex (MAC) and tuberculosis in patients with HIV infection
FDA_UNII_Code
  • 1W306TDA6S
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to prevent the spread of a bacterium called in patients with advanced HIV (the virus that causes AIDS) infection. It blocks an enzyme that the bacteria need to grow. It is a type of antibiotic.NCI-GLOSS
  • A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.MSH2002_06_01
PDQ_Open_Trial_Search_ID
  • 37812
PDQ_Closed_Trial_Search_ID
  • 37812
Chemical_Formula
  • C46H62N4O11
Legacy_Concept_Name
  • Rifabutin
CHEBI_ID
  • CHEBI:45367
FULL_SYN
  • RIFABUTINPTFDA1W306TDA6S
  • RifabutinPTNCI
  • MycobutinBRNCI
  • MycobutinPTNCI-GLOSSCDR0000663313
  • rifabutinPTNCI-GLOSSCDR0000663309
DEFINITION
  • A semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription. (NCI04)NCI
code
  • C1408
sameAs
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