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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • YXXP Motif
rdfs:subClassOf
Semantic_Type
  • Amino Acid Sequence
Preferred_Name
  • YXXP Motif
UMLS_CUI
  • C1520207
Legacy_Concept_Name
  • YXXP_Motif
FULL_SYN
  • YXXP DomainSYNCI
  • YXXP MotifPTNCI
DEFINITION
  • YXXP (tyrosine-X-X-Proline), a substrate sequence preferred by Abl tyrosine kinases, is part of the SH2 domain that mediates certain interactions of SH2 containing proteins. Although both phosphorylated- and unphosphorylated-YXXP can interacts with SH2 containing proteins, the SH2 domain obtain sufficient binding specificity from the recognition of adjacent residues to allow discrimination between different phosphorylated sites. (NCI)NCI
code
  • C14059
is someValuesFrom of
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